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Chromatin Fitting

Algorithms to fit chromatin fiber structures to OligoSTORM images.

These algorithms were developed and used for the writing of the paper:

Neguembor MV*, Arcon JP*, Buitrago D*, Lema R, Walther J, Garate X, Martin L, Romero P, AlHaj Abed J, Gut M, Blanc J, Lakadamyali M, Wu C-t, Brun Heath I, Orozco M, Dans PD, Cosma MP. MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution. Nature Struct Mol Biol. 2022.

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The repository contains the algorithms used to fit and manipulate structures at two different resolutions (chromosome and base pair). For more information, the reader is referred to the paper.

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Code used in the paper "MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution".

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