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Microracle

Microracle allows users to employ the bacterial inactivation models developed in our group with their own experimental data. Alternatively, the user can simply load the available experimental data for Escherichia coli and Bacillus cereus and modify the model parameters to test how they affect the model output.

Currently, the following models are available

  • Microbial inactivation by carvacrol at sub-MIC concentrations
    • Reference: Pedreira, et al. "Modelling the antimicrobial effect of food preservatives in bacteria: Application to Escherichia coli and Bacillus cereus inhibition with carvacrol." Journal of Food Engineering (2023). doi:10.1016/j.jfoodeng.2023.111734
  • Microbial inactivation by didecyldimethylammonium chloride (DDAC) at sub-MIC concentrations
    • Reference: Pedreira, et al. "Kinetics of bacterial adaptation, growth and death at didecyldimethylammonium chloride sub-MIC concentrations" Frontiers in Microbiology (2022). doi:10.3389/fmicb.2022.758237

Authoring

Microracle has been developed by researchers of the Biosystems and Bioprocess Engineering Group (Bio2Eng) and Recycling and Valorization of Waste Materials (REVAL) groups from the IIM-CSIC (Vigo, Spain):

  • Adrián Pedreira: Web developer, experimentation and data collection.
  • Nerea Martínez: Development of mathematical models.
  • Xosé A. Vázquez: Experimental design
  • Míriam R. García: Development of mathematical models.

For any question related to the mathematical models, please contact with Míriam R. García (miriamr@iim.csic.es) Microracle is a project in early development, so you may encounter some bugs on the web. To report any bug or a problem (https://github.com/apedreira/microracle), please generate a new issue in the GitHub repository or contact with Adrián Pedreira (apedreira@iim.csic.es).

Access

Microracle can be freely accessed from https://microracle.shinyapps.io/Microracle/. No requirements other than internet connection from a web browser are necessary.

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