diff --git a/ci-operator/config/openshift/hypershift/openshift-hypershift-release-4.23__periodics.yaml b/ci-operator/config/openshift/hypershift/openshift-hypershift-release-4.23__periodics.yaml
index 142dc28fd220c..6ef0daab3cf71 100644
--- a/ci-operator/config/openshift/hypershift/openshift-hypershift-release-4.23__periodics.yaml
+++ b/ci-operator/config/openshift/hypershift/openshift-hypershift-release-4.23__periodics.yaml
@@ -81,6 +81,11 @@ releases:
       product: ocp
       stream: nightly
       version: "4.19"
+  n1minor:
+    candidate:
+      product: ocp
+      stream: ci
+      version: "4.22"
 resources:
   '*':
     limits:
@@ -308,6 +313,16 @@ tests:
       HYPERSHIFT_AZURE_MARKETPLACE_IMAGE_SKU: ""
       HYPERSHIFT_AZURE_MARKETPLACE_IMAGE_VERSION: ""
     workflow: hypershift-azure-aks-conformance
+- as: e2e-azure-v2-self-managed
+  cron: 30 3 * * *
+  steps:
+    cluster_profile: hypershift-azure
+    dependencies:
+      OCP_IMAGE_N1: release:n1minor
+    env:
+      ENABLE_HYPERSHIFT_CERT_ROTATION_SCALE: "true"
+      HYPERSHIFT_AZURE_LOCATION: centralus
+    workflow: hypershift-azure-e2e-v2-self-managed
 - as: e2e-azure-kubevirt-ovn
   cron: 0 4 * * *
   steps:
diff --git a/ci-operator/config/openshift/hypershift/openshift-hypershift-release-5.0__periodics.yaml b/ci-operator/config/openshift/hypershift/openshift-hypershift-release-5.0__periodics.yaml
index 767e446370aa9..8c88c8236ae8a 100644
--- a/ci-operator/config/openshift/hypershift/openshift-hypershift-release-5.0__periodics.yaml
+++ b/ci-operator/config/openshift/hypershift/openshift-hypershift-release-5.0__periodics.yaml
@@ -81,6 +81,11 @@ releases:
       product: ocp
       stream: nightly
       version: "4.19"
+  n1minor:
+    candidate:
+      product: ocp
+      stream: ci
+      version: "4.22"
 resources:
   '*':
     limits:
@@ -274,6 +279,16 @@ tests:
       HYPERSHIFT_AZURE_MARKETPLACE_IMAGE_SKU: ""
       HYPERSHIFT_AZURE_MARKETPLACE_IMAGE_VERSION: ""
     workflow: hypershift-azure-aks-conformance
+- as: e2e-azure-v2-self-managed
+  cron: 30 1 * * *
+  steps:
+    cluster_profile: hypershift-azure
+    dependencies:
+      OCP_IMAGE_N1: release:n1minor
+    env:
+      ENABLE_HYPERSHIFT_CERT_ROTATION_SCALE: "true"
+      HYPERSHIFT_AZURE_LOCATION: centralus
+    workflow: hypershift-azure-e2e-v2-self-managed
 - as: e2e-azure-kubevirt-ovn
   cron: 0 4 * * *
   steps:
diff --git a/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-4.23-periodics.yaml b/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-4.23-periodics.yaml
index af89989eae233..0543202e94ea3 100644
--- a/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-4.23-periodics.yaml
+++ b/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-4.23-periodics.yaml
@@ -1261,6 +1261,89 @@ periodics:
     - name: result-aggregator
       secret:
         secretName: result-aggregator
+- agent: kubernetes
+  cluster: build07
+  cron: 30 3 * * *
+  decorate: true
+  decoration_config:
+    skip_cloning: true
+  extra_refs:
+  - base_ref: release-4.23
+    org: openshift
+    repo: hypershift
+  labels:
+    ci-operator.openshift.io/cloud: hypershift-azure
+    ci-operator.openshift.io/cloud-cluster-profile: hypershift-azure
+    ci-operator.openshift.io/variant: periodics
+    ci.openshift.io/generator: prowgen
+    job-release: "4.23"
+    pj-rehearse.openshift.io/can-be-rehearsed: "true"
+  name: periodic-ci-openshift-hypershift-release-4.23-periodics-e2e-azure-v2-self-managed
+  spec:
+    containers:
+    - args:
+      - --gcs-upload-secret=/secrets/gcs/service-account.json
+      - --image-import-pull-secret=/etc/pull-secret/.dockerconfigjson
+      - --lease-server-credentials-file=/etc/boskos/credentials
+      - --report-credentials-file=/etc/report/credentials
+      - --secret-dir=/secrets/ci-pull-credentials
+      - --target=e2e-azure-v2-self-managed
+      - --variant=periodics
+      command:
+      - ci-operator
+      env:
+      - name: HTTP_SERVER_IP
+        valueFrom:
+          fieldRef:
+            fieldPath: status.podIP
+      image: quay-proxy.ci.openshift.org/openshift/ci:ci_ci-operator_latest
+      imagePullPolicy: Always
+      name: ""
+      ports:
+      - containerPort: 8080
+        name: http
+      resources:
+        requests:
+          cpu: 10m
+      volumeMounts:
+      - mountPath: /etc/boskos
+        name: boskos
+        readOnly: true
+      - mountPath: /secrets/ci-pull-credentials
+        name: ci-pull-credentials
+        readOnly: true
+      - mountPath: /secrets/gcs
+        name: gcs-credentials
+        readOnly: true
+      - mountPath: /secrets/manifest-tool
+        name: manifest-tool-local-pusher
+        readOnly: true
+      - mountPath: /etc/pull-secret
+        name: pull-secret
+        readOnly: true
+      - mountPath: /etc/report
+        name: result-aggregator
+        readOnly: true
+    serviceAccountName: ci-operator
+    volumes:
+    - name: boskos
+      secret:
+        items:
+        - key: credentials
+          path: credentials
+        secretName: boskos-credentials
+    - name: ci-pull-credentials
+      secret:
+        secretName: ci-pull-credentials
+    - name: manifest-tool-local-pusher
+      secret:
+        secretName: manifest-tool-local-pusher
+    - name: pull-secret
+      secret:
+        secretName: registry-pull-credentials
+    - name: result-aggregator
+      secret:
+        secretName: result-aggregator
 - agent: kubernetes
   cluster: build07
   cron: 0 4 * * *
diff --git a/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-5.0-periodics.yaml b/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-5.0-periodics.yaml
index 105c5b65afee7..b5098a3460c2e 100644
--- a/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-5.0-periodics.yaml
+++ b/ci-operator/jobs/openshift/hypershift/openshift-hypershift-release-5.0-periodics.yaml
@@ -1079,6 +1079,89 @@ periodics:
     - name: result-aggregator
       secret:
         secretName: result-aggregator
+- agent: kubernetes
+  cluster: build07
+  cron: 30 1 * * *
+  decorate: true
+  decoration_config:
+    skip_cloning: true
+  extra_refs:
+  - base_ref: release-5.0
+    org: openshift
+    repo: hypershift
+  labels:
+    ci-operator.openshift.io/cloud: hypershift-azure
+    ci-operator.openshift.io/cloud-cluster-profile: hypershift-azure
+    ci-operator.openshift.io/variant: periodics
+    ci.openshift.io/generator: prowgen
+    job-release: "5.0"
+    pj-rehearse.openshift.io/can-be-rehearsed: "true"
+  name: periodic-ci-openshift-hypershift-release-5.0-periodics-e2e-azure-v2-self-managed
+  spec:
+    containers:
+    - args:
+      - --gcs-upload-secret=/secrets/gcs/service-account.json
+      - --image-import-pull-secret=/etc/pull-secret/.dockerconfigjson
+      - --lease-server-credentials-file=/etc/boskos/credentials
+      - --report-credentials-file=/etc/report/credentials
+      - --secret-dir=/secrets/ci-pull-credentials
+      - --target=e2e-azure-v2-self-managed
+      - --variant=periodics
+      command:
+      - ci-operator
+      env:
+      - name: HTTP_SERVER_IP
+        valueFrom:
+          fieldRef:
+            fieldPath: status.podIP
+      image: quay-proxy.ci.openshift.org/openshift/ci:ci_ci-operator_latest
+      imagePullPolicy: Always
+      name: ""
+      ports:
+      - containerPort: 8080
+        name: http
+      resources:
+        requests:
+          cpu: 10m
+      volumeMounts:
+      - mountPath: /etc/boskos
+        name: boskos
+        readOnly: true
+      - mountPath: /secrets/ci-pull-credentials
+        name: ci-pull-credentials
+        readOnly: true
+      - mountPath: /secrets/gcs
+        name: gcs-credentials
+        readOnly: true
+      - mountPath: /secrets/manifest-tool
+        name: manifest-tool-local-pusher
+        readOnly: true
+      - mountPath: /etc/pull-secret
+        name: pull-secret
+        readOnly: true
+      - mountPath: /etc/report
+        name: result-aggregator
+        readOnly: true
+    serviceAccountName: ci-operator
+    volumes:
+    - name: boskos
+      secret:
+        items:
+        - key: credentials
+          path: credentials
+        secretName: boskos-credentials
+    - name: ci-pull-credentials
+      secret:
+        secretName: ci-pull-credentials
+    - name: manifest-tool-local-pusher
+      secret:
+        secretName: manifest-tool-local-pusher
+    - name: pull-secret
+      secret:
+        secretName: registry-pull-credentials
+    - name: result-aggregator
+      secret:
+        secretName: result-aggregator
 - agent: kubernetes
   cluster: build07
   cron: 0 4 * * *